A Mitochondrial Paradigm for Degenerative Diseases, Aging and Cancer: Why do we still have a Maternally Inherited Mitochondrial DNA?
Douglas Wallace (University of California, Irvine)
Dr. Wallace is one of the nation s leading genetics researchers, helping to discover how defects in inherited genes contribute to neurodegenerative diseases such as Parkinson s and Alzheimer s. Through his research, Wallace has shown that defects in mitochondrial genes are major contributors to degenerative diseases, cancer and aging. A recent study of his, published in the Proceedings of the National Academy of Sciences, shows a link between mitochondrial DNA mutations and prostate cancer. He's using that link now to test non-toxic drugs to kill prostate cancer in mice.
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