The Huck Institutes of the Life Sciences

Bioinformatics and Genomics News

Marylyn Ritchie, professor of biochemistry and molecular biology and director of the Center for Systems Genomics in the Huck Institutes of the Life Sciences at Penn State University, will lead a collaborative effort between Penn State and Geisinger Research to connect the genome data of 100,000 anonymous patients with their medical histories, in order to identify the genetic and environmental basis of human disease.
Inhibiting a nuclear receptor in the gut could lead to a treatment for a liver disorder that affects almost 30 percent of the Western world's adult population, according to an international team of researchers.
Manuel Llinás, a Huck-cofunded researcher and associate professor of biochemistry and molecular biology at Penn State has been awarded two years of Phase II funding for a Grand Challenges Exploration Grant from the Bill and Melinda Gates Foundation.
New genetic research reveals that a small group of hunter-gatherers now living in Southern Africa once was so large that it comprised the majority of living humans during most of the past 150,000 years.
Powerful clues have been discovered about why the human immune system, metabolism, stress response, and other life functions are so different from those of the mouse.
The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells — and the transmission of these mutations to children — could provide valuable insights for genetic counseling.
Molecular, Cellular, and Integrative Biosciences Ph.D. candidate Marta Byrska-Bishop and faculty researcher Dr. Ross Hardison study genomics and gene regulation in relation to inherited diseases.
Huck scientists find Theobroma cacao trees' natural disease defense is bolstered by glycerol foliar treatment
Digital epidemiologist Marcel Salathe is teaching an online infectious disease course that he designed to be fun, and the knowledge is spreading like a virus.
Researchers at the Center for Systems Genomics are developing bioinformatics software to facilitate analysis of rare variation in human genome sequence data.
Huck Institutes affiliate Kateryna Makova, a professor of biology at Penn State, has been honored by the University's Eberly College of Science by being appointed the Francis R. and Helen M. Pentz Professor of Science.
The Huck Institutes are pleased to announce a new fund to provide research support for students in our graduate programs.
Huck Institutes researcher Moriah Szpara takes an interdisciplinary tack in her work -- using tools from neurobiology, virology, bioinformatics, and comparative genomics to find keys to a cure for human herpesvirus.
Beetles with unusual "green thumbs" for growing fungi are threatening avocado crops and could transform into a more destructive pest, according to an international team of researchers that includes Huck Institutes affiliate David Geiser.
Medicines that are personally tailored to your DNA are becoming a reality, thanks to the work of U.S. and Chinese scientists including Huck Institutes affiliate Rongling Wu who have developed statistical models to predict which drug is best for a specific individual with a specific disease.
Researchers including Huck Institutes affiliate Wansheng Liu have found that, surprisingly, the Y chromosomes of cattle have more genes and are more active than the Y chromosomes of a variety of primates and other mammals.
While we tend to think of viruses as nasty germs that we try desperately to get rid of, only a small percentage of viruses are pathogens, said Huck Institutes affiliate Marilyn Roossinck in a recent presentation at the Millennium Cafe.
Claude dePamphilis has been selected to receive the 2013 Penn State Faculty Scholar Medal for Outstanding Achievement in the Life and Health Sciences.
Ruowang Li has been awarded a Graduate Research Fellowship by the National Science Foundation (NSF) for his proposal to combine genomics, statistics, and machine learning in a multidisciplinary approach to studying genetic factors that influence cellular response to chemotherapy drugs.
Research by Huck Institutes affiliate Eric Harvill suggests that managing bacteria and other microorganisms in the body, rather than just fighting them, may be lead to better health and a stronger immune system.