The Huck Institutes of the Life Sciences

Molecular mass determination of small molecules

Molecular mass determination services provided by the Proteomics and Mass Spectrometry Core Facility at University Park


  • Confirmation of reaction products
  • Nominal mass and accurate mass measurements (<10ppm)
  • Analysis of synthetic compounds, polymers and biomolecules (intact proteins (<60KDa), peptides, lipids (<1KDa), and oligonucleotides)
  • Ionization methods:  ESI(+/-), APCI (+/-), CI (+)
  • Mixture analysis by LC-MS and LC MS-MS