The Huck Institutes of the Life Sciences

Dynamic light scattering

Dynamic light scattering service provided by the X-Ray Crystallography Facility
  • Analysis of variables such as aggregation, folding and conformation as a function or time and/or treatment.
  • Dynamic light scattering is a technique in which a beam of monochromatic light is directed through a biomolecule solution; fluctuations in scattered light intensity are analyzed.
  • A dynamic light scattering experiment is non-invasive, and can quickly provide information about size and homogeneity of  biomolecules. With this size information, sample characteristics like aggregation, folding, or conformation can be monitored as a function of various preparations, solvent conditions, temperature, or time.

Instrumentation

Viscotek 802 Dynamic Light Scattering Instrument
A state-of-the-art dynamic light scattering instrument matched with powerful but user friendly OmniSIZE software to give the most sensitive and accurate hydrodynamic radius