The Huck Institutes of the Life Sciences

Center for Cellular Dynamics Labs

Research laboratories that are part of the Center for Cellular Dynamics
  • Anderson lab

    Anderson lab

    Charlie Anderson's lab studies the synthesis, modification, and degradation of plant cell walls.

     

  • Bai lab

    Bai lab

    Lu Bai's lab studies chromatin and gene regulation at the single-cell and single-molecule level.

  • Bell lab

  • ATP biosensor imaging of epithelial-to-mesenchymal transition

  • In the Bell lab, we aim to understand how cells regulate metabolism to maintain homeostasis while executing the energetically demanding mechanical work involved in cell migration. Currently, we are using biochemical and live cell biosensor imaging approaches to study cellular energetics during epithelial-to-mesenchymal transition and cancer cell migration. Altering the physical environment of cells through increased confinement can change the energetic demands involved in migration, and result in different activation and requirements for metabolic pathways.

    In cancer, the normal regulatory responses that control cell metabolism are often disrupted, so we are also interested in determining whether the migratory behavior of metastatic cancer cells results in increased susceptibility to therapies targeting metabolic pathways.

  • Belmonte lab

    image from Belmonte lab

Andrew Belmonte's group develops mathematical models using game theory and population dynamics to describe cellular signaling pathways, cancer, and for interactions involving competition, cooperation and migration.

  • Cavener lab

    Cavener lab

    Doug Cavener's lab studies metabolism, endoplasmic reticulum function and diabetes using mouse models.

     

  • Chen lab

    Chen lab

    The focus of research in Gong Chen's lab is neuronal polarity and synapse formation. The lab is also interested in endocytic pathways in neurons and glia.

     

  • Gu lab

    Gu lab

    Ying Gu's lab studies cellulose biosynthesis and regulation in model plant Arabidopsis.

     

  • Hancock lab

    Hancock lab

    Will Hancock's lab studies the biomechanics of kinesin molecular motors.

     

  • Hanna-Rose lab

    Hanna-Rose lab

    Wendy Hanna-Rose's lab uses C. elegans as a model to study the cell biology of development.

     

  • Jegla lab

    Jegla lab

    Tim Jegla's lab is interested in how potassium channels modulate neuronal excitability.

     

  • Lai lab

    Lai lab

    In Zhi-Chun Lai's lab we study the control of tissue growth and organ size by the Hippo signaling pathway.

     

  • Liu lab

    Liu lab

    Aimin Liu's lab studies cilia biogenesis and mouse development.

     

  • Luscher lab

    Luscher lab

    Bernhard Luscher's lab studies the structure and function of GABAergic inhibitory synapses.

     

  • Mao lab

    Mao lab

    Yingwei Mao's lab studies mechanisms underlying neurogenesis in development and disease.

     

  • Mastro lab

    Mastro lab

    Andrea Mastro's lab studies the process by which breast cancer cells colonize bone.

     

  • Monshausen lab

    Monshausen lab

    Research in Gaby Monshausen's lab focuses on how plants receive and respond to external stimuli.

     

  • Nader lab

    Nader lab

    The Nader Lab studies skeletal and cardiac muscle size control with a focus on the cellular and molecular mechanisms regulating ribosome biogenesis

     

  • Ordway lab

    Ordway lab

    Rick Ordway's lab investigates molecular mechanisms of synaptic transmission.

     

  • Rolls lab

    Rolls lab

    In Melissa Rolls' lab we study neuronal polarity and neuronal responses to injury.

     

  • Santy lab

    Santy lab

    Lorraine Santy's lab investigates small GTPase regulation of epithelial cell migration.

     

  • Thomas lab

    Thomas lab

    Claire Thomas' lab studies the cortical spectrin/F-actin cytoskeleton and its role in the control of cell polarity, adhesion and vesicular trafficking.