The Huck Institutes of the Life Sciences


Grant proposals to the W.M. Keck Foundation continue

The initiative is ongoing, with a 3-5 year target for successful awards; the next submission cycle begins November 1, 2012.

Current grant cycle overview

Grant cycle timeline for awards to be determined December 2012
Pre-application counseling

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New BioChip may make diagnosis of leukemia and HIV faster and cheaper

Tony Jun Huang and his colleagues, including Wafik El-Deiry, have developed a faster, cheaper and portable alternative to the current flow cytometry technology used to diagnose HIV and leukemia.

Flow cytometry is a laser-based, biophysical technology employed in cell counting and sorting, biomarker detection, and protein engineering — which applications are also of use in clinical diagnosis and tracking the progression of diseases such as cancer and HIV/AIDS.

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Two Penn State biomedical researchers receive a Gates Foundation grant

Andrew Patterson and Gary Perdew have been awarded a grant from the Grand Challenges Explorations program to test their approach toward reducing illness and death from gastrointestinal diseases in infants and children.

In their proposal, entitled "Modulation of aryl hydrocarbon recepter (AHR) activity for establishing and maintaining gut immune function and overall intestinal health," the two researchers postulate that these illnesses and deaths can be reduced through dietary modification or supplementation tha

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A strategy is discovered to activate genes that suppress cancer

A team of researchers led by Yanming Wang of the Huck Institutes' Center for Eukaryotic Gene Regulation and Gong Chen of the Department of Chemistry has found that by inhibiting the PAD4 enzyme they can reactivate tumor-suppressing genes to destroy cancerous cells.

Building on previous research, Dr.

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Penn State researcher plays a role in the discovery of a leukemia gene mutation

Thomas Loughran " director of the Penn State Hershey Cancer Institute and discoverer of large granular lymphocyte (LGL) leukemia " is part of an international research team that has found a gene mutation underlying the rare malignant cancer.

The team discovered that roughly 40 percent of LGL leukemia patients have a non-inherited mutation in the STAT3 gene that causes it to remain in a perpetual state of activity.

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A decade's worth of research suggests that fish feel pain

Victoria Braithwaite discusses the need for better aquaculture practices in designing healthier and more humane fisheries.

Dr. Braithwaite was recently interviewed by Melissa Beattie-Moss for Research Penn State, and discussed the implications of her research for anglers, farmers, activists and consumers.

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Eco-immunology charts pathways of disease in nature

Huck Institutes director Peter Hudson and researcher Raina Plowright of the Center for Infectious Disease Dynamics have been featured in the New York Times for their research on disease ecology in bighorn sheep and Australian fruit bats.

The article, entitled "In Wild Animals, Charting the Pathways of Disease," ran Tuesday, May 29, 2012 in the Science Times section, and

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U.S. Secretary of Agriculture highlights importance of agricultural education and research

Tom Vilsack traveled to Penn State to commemorate the 150th anniversary of the U.S. Department of Agriculture and the land-grant university system " highlighting the groundbreaking research, education, and innovation taking place nationwide at universities such as Penn State.

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Patrick Drew receives a 2012 McKnight Scholar Award

The Board of Directors of The McKnight Endowment Fund for Neuroscience has announced the 2012 McKnight Scholar Award recipients " among them Penn State professor and Huck Institutes faculty member Patrick Drew with his proposal entitled "Imaging neurovascular coupling in the behaving animal."

About Patrick Drew

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David Hughes receives a Grand Challenges Explorations grant from the Bill & Melinda Gates Foundation

The Penn State biology and entomology professor and Huck Institutes faculty member has been granted funding to pursue his innovative global health and development research project, entitled "Taking out the bodyguards: a novel solution to ag disease."

About the award

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Researchers unveil a new assessment for diagnosing malnutrition

A team of researchers " led by Penn State professor and Huck Institutes faculty member Gordon Jensen " has devised a new systematic assessment that should aid dietitians and other health care providers in diagnosis and treatment.

This new approach to diagnosis describes symptoms of malnutrition in the context of starvation, chronic and acute disease, and injury — each of which may contribute to malnutrition through inflammatory response and resulting loss of appetite, abnormal absorption, and muscle breakdown — and provid

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Patrick Drew is working toward a better understanding of the brain's complex infrastructure

He can't see inside your brain, but Dr. Drew has found a way to see inside a mouse's brain and by doing so, he is gaining new insights into how the human brain may function.

By grinding down the skull to the point of translucence, then polishing the skull and reinforcing it with protective glass, Dr.

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Philip C. Bevilacqua is awarded the C.I. Noll Award for Excellence in Teaching

Dr. Bevilacqua, a professor of chemistry at Penn State and co-director of the Huck Institutes' Center for RNA Molecular Biology, has been honored by the Eberly College of Science Alumni Society with the 2012 C.I. Noll Award for Excellence in Teaching.

The C.I. Noll Award

Instituted in 1972 and named in honor of Clarence I. Noll, dean of the college from 1965 to 1971, the award is the highest honor for undergraduate teaching in the college.

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Biological battle: Penn State researchers work to catch up with drug resistance

Written by Andrew Read " director of the Huck Institutes' Center for Infectious Disease Dynamics " this article originally appeared in the Centre Daily Times on April 29, 2012 as the first installment of the bimonthly "Focus on Research" column highlighting research projects being conducted across all disciplines at Penn State.

Evolution kills.

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Reese and Bevilacqua advisees travel beyond Penn State to showcase research

Jason Miller, Chris Strulson, Jenny Wilcox, Pallavi Thaplyal and Kwok Chun Kit present their work to researchers at several other respected institutions.

Jason Miller, a graduate student in the Reese lab, attended the "Systems Biology: Global Regulation of Gene Expression" meeting this past March at Cold Spring Harbor Laboratories, where he presented a poster entitled "Identification of targets of mRNA decay factors using RIP-seq reveals they targ

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Twenty-four new species of lizards discovered on Caribbean islands are close to extinction

A research team led by Penn State biology professor and Huck Institutes faculty member Blair Hedges has identified and named 24 new species of skinks " half of which may already be extinct or nearing extinction, and the rest of which are threatened with extinction.

Furthermore, Dr. Hedges' research suggests that all of the skink species found exclusively in the Caribbean islands are threatened and should be listed as either vulnerable, endangered, or critically endangered.

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Binge eating may lead to other addiction-like behaviors

Researchers at the Penn State Hershey College of Medicine " including Huck Institutes faculty member Patricia Grigson " find that a history of binge eating may make an individual more likely to exhibit other addiction-like behaviors including substance abuse.

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Penn State joins the 2012 Dow Sustainability Innovation Student Challenge Award program

The program is designed to promote forward thinking in social and environmental responsibility, and acknowledges the energy, commitment and enthusiasm of students and their professors who support their innovations.

Beginning in 2012, Penn State has been invited to join the set of universities participating in the program.

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Life Technologies' Ion Bus comes to Penn State

On its way from Pittsburgh to Philadelphia, the Bus makes a stop in Happy Valley to showcase its genome sequencing technology.

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Exercise and attitude may be thermostat for hot flashes

Penn State professor Steriani Elavsky " a Huck Institutes faculty member in the Institute for Diabetes and Obesity " postulates that affective outcomes and perceived control may help to potentially explain significant variability in the impact of physical activity on hot flashes.

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